Cocamidopropyl betaineby Naturallythinking Safety Data Sheet (SDS)

SDS for Cocamidopropyl betaine

Safety Data Sheet (SDS) dated 29/11/2023

Batch Number: FRAMECPSR

Section 1: Identification of Product and Supplier

Product Name: Cocamidopropyl betaine
Product Number: 5060330630570
Brand: Naturallythinking
UK: Naturallythinking, Unit 2 Mill Lane Trading Estate, Mill Lane, Croydon, CR0 4AA
EU: NTEU Ltd (HE 426545), Nikis 1, Anthoupoli, 2350, Nicosia, Cyprus
Contact Telephone: 020 38563588
Contact Email:

Section 2: Hazards IDENTIFICATION

2.1 Classification of the substance or mixture


Human Health
Skin. Irrit. 2 - H315; Eye. Dam. 2A - H319

2.2 Label elements According to Regulation (EC) No. 1272/2008 (CLP)

2.2.1 Label elements

GHS Product Identifier: Cocamidopropyl betaine

Hazard pictogram(s)


Causes skin irritation
Causes serious eye irritation
Very toxic to aquatic life




Section 3: Composition and information on Ingredients

Inci: Cocamidopropyl betaine
Cas: 61789-40-0
Einecs: 263-058-8

3.1. Substances


3.2. Mixtures

Product type and use: Sufactants 
Hazardous components within the meaning of the CLP regulation and related classification:

Qty Name Ident. Number Classification
>= 30% - < 40% Cocamidopropyl betaine CAS: 147170-443
EC: 931333-8
REACH: 01-2119489410-39-XXX
3.3/1 Eye Dam.1 H318
4.1/C3 Aquatic Chronic 3 H412
>= 1% - < 3% Coconut fatty acids CAS: 61788-47-4
EC: 262-978-7
3.3/2 Eye Irrit. 2 H319
3.2/2 Skin Irrit. 2 H315
>= 0.25% - < 0.5% Cocco, N-[3- (dimetilamino)propil] ammide  CAS: 68140-01-2
EC: 268-771-8
3.1/4 Oral Acute Tox. 4H320
4.1/A1 Aquatic Acute 1 H400


Section 4: First aid measures

4.1. Description of first aid measures

In case of skin contact:

Immediately take off all contaminated clothing. Areas of the body that have - or are only even suspected of having - come into contact with the product must be rinsed immediately with plenty of running water and possibly with soap. OBTAIN IMMEDIATE MEDICAL ATTENTION. Wash thoroughly the body (shower or bath). Remove contaminated clothing immediately and dispose off safely.

In case of eyes contact:

After contact with the eyes, rinse with water with the eyelids open for a sufficient length of time, then consult an opthalmologist immediately. Protect uninjured eye.

In case of Ingestion:

Do not under any circumstances induce vomiting. OBTAIN A MEDICAL EXAMINATION IMMEDIATELY.

In case of Inhalation:

Remove casualty to fresh air and keep warm and at rest.

4.2. Most important symptoms and effects, both acute and delayed


4.3. Indication of any immediate medical attention and special treatment needed

In case of accident or unwellness, seek medical advice immediately (show directions for use or safety data sheet if possible). Treatment: None 

Section 5: Fire - Fighting measures

5.1. Extinguishing media

Suitable extinguishing media:

Carbon dioxide (CO2).
Extinguishing media which must not be used for safety reasons: None in particular.

5.2. Special hazards arising from the substance or mixture

Do not inhale explosion and combustion gases. Burning produces heavy smoke.

5.3. Advice for firefighters Use suitable breathing apparatus.

Collect contaminated fire extinguishing water separately. This must not be discharged into drains.
Move undamaged containers from immediate hazard area if it can be done safely

Section 6: Accidental release measures

6.1. Personal precautions, protective equipment and emergency procedures

Wear personal protection equipment. Remove persons to safety. See protective measures under point 7 and 8.

6.2. Environmental precautions

Do not allow to enter into soil/subsoil. Do not allow to enter into surface water or drains. Retain contaminated washing water and dispose it. In case of gas escape or of entry into waterways, soil or drains, inform the responsible authorities. Suitable material for taking up: absorbing material, organic, sand

6.3. Methods and material for containment and cleaning up Wash with plenty of water.

6.4. Reference to other sections See also section 8 and 13

Section 7: Handling and Storage

7.1. Precautions for safe handling

Avoid contact with skin and eyes, inhalation of vapours and mists. Don't use empty container before they have been cleaned. Before making transfer operations, assure that there aren't any incompatible material residuals in the containers. Contamined clothing should be changed before entering eating areas. Do not eat or drink while working. See also section 8 for recommended protective equipment.

7.2. Conditions for safe storage, including any incompatibilities

Storage recommended at room temperature Keep away from food, drink and feed. Incompatible materials: None in particular.

Instructions as regards storage premises:

Adequately ventilated premises.

7.3. Specific end use(s) None in particular

Section 8: Exposure controls and personal protection

8.1. Control parameters

No occupational exposure limit available

DNEL Exposure Limit Values


PNEC Exposure Limit Values


8.2. Exposure controls

Eye protection:

Safety glasses with side-shields (frame goggles) (e.g. EN 166)

Protection for skin:

Use clothing that provides comprehensive protection to the skin, e.g. cotton, rubber, PVC or viton.

Protection for hands:

Chemical resistant protective gloves (EN 374) Suitable materials also with prolonged, direct contact (Recommended: Protective index 6, corresponding > 480 minutes of permeation time according to EN 374) 

Respiratory protection:

Suitable respiratory protection for higher concentrations or long-term effect: Particle filter with medium /high efficiency for solid particles (e.g. EN 143 or 149, Type P2 or FFP2)

Thermal Hazards: None Environmental exposure controls:


Appropriate engineering controls:


Section 9: Physical data and chemical properties

9.1. Information on basic physical and chemical properties

Properties Value Method  
Appearance and colour LIQUID YELLO -- --
Odour Characteristic -- --
Odour threshold N.A. -- --
pH 5 -- --
Melting point / freezing point -5 degrees C -- --
Initial boiling point and boiling range 100 degrees C -- --
Flash point: > 100 degrees C -- --
Evaporation rate: N.A. -- --
Soild / gas flammability N.A. -- --
Upper / lower flammability N.A. -- --
Vapour pressure N/A/ -- --
Vapour density N.A. -- --
Relative density 1.05 -- --
Solubility in water soluble -- --
Solubility in oil insoluble -- --
Partition coefficient (n-octanol/water) N.A. -- --
Auto-ignition temperature N.A. -- --
Decomposition temperature N.A. -- --
Viscosity N.A. -- --
Explostive properties N.A. -- --
Oxidising properties N.A. -- --

9.2. Other information

Properties Value Method  
Miscibility N.A. -- --
Fat Solubility N.A. -- --
Conductivity N.A. -- --
Substance Groups relevant properties N.A. -- --


Section 10: Stability & Reactivity

10.1. Reactivity

Stable under normal conditions

10.2. Chemical stability

Stable under normal conditions

10.3. Possibility of hazardous reactions 


10.4. Conditions to avoid

Stable under normal conditions.

10.5. Incompatible materials

None in particular.

10.6. Hazardous decomposition products


Section 11: Toxicological Information

11.1. Information on toxicological effects

Toxicological information of the product:

a) acute toxicity

Not classified
Based on available data, the classification criteria are not met

b) skin corrosion/irritation

Not classified
Based on available data, the classification criteria are not met

c) serious eye damage/irritation

The product is classified: Eye Dam. 1 H318

d) respiratory or skin sensitisation

Not classified
Based on available data, the classification criteria are not met

e) germ cell mutagenicity

Not classified
Based on available data, the classification criteria are not met

f) carcinogenicity

Not classified
Based on available data, the classification criteria are not met

g) reproductive toxicity

Not classified
Based on available data, the classification criteria are not met

h) STOT-single exposure

Not classified
Based on available data, the classification criteria are not met

i) STOT-repeated exposure

Not classified
Based on available data, the classification criteria are not met

j) aspiration hazard

Not classified
Based on available data, the classification criteria are not met

Toxicological information of the main substances found in the product:

Cocamidopropyl betaine - CAS: 147170-44-3

a) acute toxicity:
Test: LD50 - Route: Oral - Species: Rat
8100 mg/kg

c) serious eye damage/irritation:
Test: Eye Irritant - Species: Rabbit

d) respiratory or skin sensitisation:
Test: Skin Sensitization - Species: Guinea pig

e) germ cell mutagenicity:
Test: Mutagenesis - Species: Rabbit Negative
Coconut fatty acids - CAS: 61788-47-4
Acute oral toxicity LD50 (rat) > 2000 mg/Kg

Section 12: Ecological information

12.1. Toxicity

Adopt good working practices, so that the product is not released into the environment.

The product is classified: Aquatic Chronic 3 - H412

Cocamidopropyl betaine - CAS: 147170-44-3

a) Aquatic acute toxicity:
Endpoint: LC50 - Species: Fish 25 mg/l - Duration h: 25
Endpoint: EC50 - Species: Daphnia 45 mg/kg - Duration h: 45

12.2. Persistence and degradability


Biodegradability: Readily biodegradable - Test: N.A. - Duration: N.A. - %: N.A. - Notes:
Regulation (EC) No. 648/2004

12.3. Bioaccumulative potential


12.4. Mobility in soil


12.5. Results of PBT and vPvB assessment

vPvB Substances: None - PBT Substances: None

12.6. Other adverse effects



Section 13: Disposal considerations

13.1. Waste treatment methods

Recover, if possible. Send to authorised disposal plants or for incineration under controlled conditions. In so doing, comply with the local and national regulations currently in force. 

Section 14: Transport information

14.1. UN number

Not classified as dangerous in the meaning of transport regulations.

14.2. UN proper shipping name


14.3. Transport hazard class(es)


14.4. Packing group


14.5. Environmental hazards Marine pollutant:


14.6. Special precautions for user


14.7. Transport in bulk according to Annex II of Marpol and the IBC Code


Section 15: Regulatory information

15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture

Dir. 98/24/EC (Risks related to chemical agents at work)

Dir. 2000/39/EC (Occupational exposure limit values)

Regulation (EC) n. 1907/2006 (REACH)

Regulation (EC) n. 1272/2008 (CLP)

Regulation (EC) n. 790/2009 (ATP 1 CLP) and (EU) n. 758/2013

Regulation (EU) 2015/830 Regulation (EU) n. 286/2011 (ATP 2 CLP)

Regulation (EU) n. 618/2012 (ATP 3 CLP)

Regulation (EU) n. 487/2013 (ATP 4 CLP)

Regulation (EU) n. 944/2013 (ATP 5 CLP) Regulation (EU) n. 605/2014 (ATP 6 CLP)

Regulation (EU) n. 2015/1221 (ATP 7 CLP)

Restrictions related to the product or the substances contained according to Annex XVII Regulation (EC) 1907/2006 (REACH) and subsequent modifications: 

Where applicable, refer to the following regulatory provisions :

Directive 2012/18/EU (Seveso III)

Regulation (EC) nr 648/2004 (detergents).

Dir. 2004/42/EC (VOC directive)

Provisions related to directive EU 2012/18 (Seveso III):

Seveso III category according to Annex 1, part 1 None

15.2. Chemical safety assessment

No Chemical Safety Assessment has been carried out for the mixture. Substances for which a Chemical Safety Assessment has been carried out: None

Section 16: Other information

Text of phrases referred to under heading 3:

H318 Causes serious eye damage.
H412 Harmful to aquatic life with long lasting effects.
H319 Causes serious eye irritation.
H315 Causes skin irritation.
H302 Harmful if swallowed.
H400 Very toxic to aquatic life

Hazard class and hazard category Code Description
Actue Tox. 4 3.1/4 Acute toxicity (oral), Category 4
Skin Irrit. 2 3.2./2 Skin irritation, Category 2
Eye Dam. 1 3.3/1 Serious eye damage, Category 1
Eye Irrit. 2 3.3/2 Eye irritation, Category 2
Aquatic Acute 1 4.1/A1 Acute aquatic hazard category 1
Aquatic Chronic 3 4.1/C3 Chronic (long term) aquatic hazard, category 3

Classification and procedure used to derive the classification for mixtures according to Regulation (EC) 1272/2008 [CLP]: 

Classification according to Regulation (EC) Nr. 1272/2008 Classification procedure 
Eye Dam. 1, H318 Calculation method
Aquatic Chronic 3, H412 Calculation method

Main bibliographic sources: ECDIN - Environmental Chemicals Data and Information Network - Joint Research Centre, Commission of the European Communities SAX's DANGEROUS PROPERTIES OF INDUSTRIAL MATERIALS - Eight Edition - Van Nostrand Reinold

This MSDS cancels and replaces any preceding release.

GMO Declaration

We declare that at present all our regisered and commercially available ingredients, extracts, oils, plants and skincare products are derived by traditional plant breeding methods. We do not have any ingredient, extract, oil or skincare product from genetically modified material

To the best of our knowledge, the information contained in the sheet is correct. However, we cannot accept responsibility for any consequences from its use.

Animal Testing Declaration

UK: As set out under the conditions in Schedule 34 - Amendment of Regulation (EC) No 1223/2009 and related amendments of The Product Safety and Metrology etc. (Amendment etc.) (EU Exit) Regulations 2019 neither the cosmetic nor its component product has been tested on animal purposes

EU:As set out in under the conditions in 1223/2009. Art. 15 Nar. Parliament and the Council of the EU 952/2013 neither the cosmetic nor its component product has been tested on animal purposes


We believe there is already a “safe” and known group of product ingredients used in the cosmetics industry which leave enough scope to be creative and innovative in product formulation without the need for anymore animal testing on new experimental ingredients.

Our suppliers each also agree to not to carry out animal testing on the products and ingredients we purchase. We have a self-imposed cut-off date of 2006 (this was the date our cosmetic formulations came into being) although in reality our suppliers normally have animal testing dates far in excess of this or have never tested at all.

We do not conduct any form of animal testing.

We do not commission any form of animal testing from a third party.

We operate a fixed cut-off date for animal testing and ingedients, which means we will not use any ingredient that has been tested or retested on animals for cosmetics purposes since January 1, 2006

If we find that a company is involved in animal testing in anyway that purchases from us, then we will cease supply immediately. It is a term and condition that by purchasing from Naturallythinking you will not involve yourself or your company in any form of Animal Testing, any violation of this will be dealt with as per any violation of our terms and condtions